Selective candidate generation
Computational candidate design where selectivity is a structural constraint from the first step — not a filter applied after synthesis.
I design computational methods for selective candidate discovery and for finding structure in clinical and biological data.
Computational candidate design where selectivity is a structural constraint from the first step — not a filter applied after synthesis.
Information-theoretic analysis of clinical trajectories and outcome distributions, identifying dynamics within individual domains and detecting treatment signals that standard analytical frameworks are not structured to reach.
My work uses novel, peer-reviewed methodology built to route around known limitations in conventional analytical approaches. Standard methods work as conventionally deployed, but they also inherit conventional constraints. I engineer tools for each engagement, built from the problem up, to reach data structure and selectivity targets that those constraints put out of reach.
Independence at Auqxana is deliberately maintained. No institutional overhead, no long turnaround times. You work directly with me, and I bring the research perspective and dedicated time your problem actually requires.
Whether the need is clinical data analysis, computational chemical design, or fundamental research, Auqxana works from an information-theoretic and dynamical-systems foundation.
Rodriguez, A.M. (2026). An entropy-initiated coupled-trait ODE framework for modeling longitudinal cohort dynamics. PLOS ONE 21(3), e0344090. doi:10.1371/journal.pone.0344090
Rodriguez, A.M. (2026). Geodesic costs on a scalar field over the periodic table predict diatomic bond dissociation energies. Discover Chemistry (accepted). preprint
Rodriguez, A.M. (2026). Shannon entropy trajectories reveal between-arm distributional structure invisible to standard endpoint analysis in pooled ALS clinical trials. medRxiv. doi:10.64898/2026.04.20.26351319
Reach out to start a discussion on how I can help with your toughest analytics needs.